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Job - Arctoris

Senior Scientific Data Scientist

permanent Hybrid (Office/Remote)

Company/ Role Overview

Arctoris is seeking a Senior Scientific Data Scientist / Pipeline Engineer to design, implement, and maintain the analytical pipelines that power our data-driven drug discovery platform.

This role is ideal for a scientist-turned-coder or data scientist with strong Python skills, statistical modelling expertise, and experience with bioassay data - paired with solid software engineering discipline.  

If you thrive at the intersection of biology, data, and scientific automation, enjoy partnering with wet-lab teams, and want to build robust tools that accelerate therapeutic discovery, this is the ideal opportunity.

Main Responsibilties

Scientific Analysis & Pipeline Development

  • Build, maintain, and extend Python-based analytical pipelines for diverse bioassay datasets (biochemical, biophysics, and cell-based assays).

  • Implement robust statistical and modelling workflows, including:

    • dose–response modelling and curve fitting (e.g., 4PL, mechanistic models)

    • QC and normalisation frameworks

    • plate-level statistics and data validation

  • Translate scientist workflows into reproducible, automated analysis pipelines.

Data Engineering & Workflow Structuring

  • Design structured ETL/ELT processes for experimental data ingestion, curation, and transformation.

  • Develop clean, maintainable, well-tested Python codebases using solid software engineering principles.

  • Use lightweight workflow tools (e.g., Snakemake, Luigi, or similar) to organise multi-step scientific analyses.

Scientific Collaboration & Communication

  • Partner closely with wet-lab scientists to:

    • understand assay logic and experimental design

    • identify improvements to data structures and analysis readiness

    • streamline file preparation and data handover

  • Provide input on experimental interpretation where it helps clarify analytical or QC decisions.

Infrastructure & Tooling (Nice-to-Have)

  • Support backend integration with cloud storage or databases (AWS S3, PostgreSQL, etc.).

  • Contribute to internal scientific tooling, dashboards, or lightweight GUIs (optional).

  • Assist with continuing evolution of scientific data architecture.

Qualifications and Experience

Scientific & Analytical

  • Strong experience analysing plate-based bioassay data (384- or 1536-well formats).

  • Proficiency in Python for scientific computing, including NumPyPandasSciPy, curve fitting libraries such as lmfit, and visualisation libraries such as Matplotlib/Seaborn. Experience with scikit-learn for exploratory analysis (e.g., PCA, clustering), data validation tools (e.g., Pandera), and scientific libraries such as Biopython or RDKit is highly beneficial.

  • Solid understanding of statistical modelling, curve fitting, and QC in experimental biology.

  • Ability to work across multiple scientific domains and adapt to varied assay formats.

Software Engineering

  • Proficient in:

    • modular design and code organisation

    • testing (PyTest/Unittest)

    • version control (Git)

    • clear documentation and reproducibility

  • Experience developing end-to-end data or analysis pipelines.

Collaboration & Communication

  • Able to work fluidly across scientific teams and translate scientific needs into computational workflows.

  • Clear and structured communicator; capable of articulating analytical choices and modelling approaches.

  • Strong problem-solving mindset.

Desirable Skills

  • Experience with lightweight workflow managers (e.g., Snakemake, Luigi).

  • Familiarity with AWS or cloud storage systems.

  • Database experience (PostgreSQL/MySQL) and data modelling.

  • Background in biophysics, cell biology, enzymology, or other relevant scientific domains.

  • Exposure to containerisation (Docker) or CI/CD (GitHub Actions). 

  • Ability to develop simple user-facing interfaces (e.g., Streamlit).

About us
Arctoris is a tech-enabled biopharma platform company founded and headquartered in Oxford, UK with its US operations based in Boston and its Asia-Pacific operations based in Singapore. Arctoris combines robotics and data science with a world-class team for small molecule and biologics discovery.